同卵双生子对照设计的生物统计学遗传分析
Biometrical genetic analysis of the cotwin control design.
作者信息
Duffy D L
机构信息
Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Australia.
出版信息
Behav Genet. 1994 Jul;24(4):341-4. doi: 10.1007/BF01067535.
PMID:7993312
Abstract
The twin-cotwin matched case-control design can be interpreted in terms of bivariate genetic factor models. I derive expressions for the expected intrapair difference for a trait correlated with the variable on which discordance was selected.
摘要
双胎-双胎匹配病例对照设计可以根据双变量遗传因子模型来解释。我推导了与选择不一致的变量相关的性状的预期配对内差异的表达式。
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