Biémont C, Lemeunier F, Gautier C, Garcia Guerreiro M, Aulard S, Pasyukova E G
Laboratoire de Biométrie, Génétique, Biologie des populations, URA CNRS 243, Université Lyon I, Villeurbanne, France.
C R Acad Sci III. 1994 Mar;317(3):213-6.
We have analysed by in situ hybridization the insertion site polymorphism of the copia, mdg1, mdg3, and P transposable elements in diploid genomes of wild males from a natural population of Drosophila melanogaster. The values of observed average degree of individual heterozygosity for all elements except mdg3 deviate statistically from the values expected by site frequencies, revealing a tendency toward homozygosity as if drift or a structuration in the population was operating. The high degree of heterozygosity for mdg3 which in addition does not deviate from the expected value, suggests that recent high rate of movements has strongly countered the population host effect on this element. Hence, heterozygosity for TEs may well reflect the history of the population, and reveals temporary high rate of site movement existing in natural populations.
我们通过原位杂交分析了来自黑腹果蝇自然种群的野生雄性二倍体基因组中copia、mdg1、mdg3和P转座元件的插入位点多态性。除mdg3外，所有元件观察到的个体杂合度平均程度值在统计学上偏离了位点频率预期值，显示出纯合化趋势，就好像种群中存在漂变或结构形成。mdg3的高杂合度且未偏离预期值，表明近期的高移动率有力地抵消了种群宿主对该元件的影响。因此，转座元件的杂合度很可能反映了种群历史，并揭示了自然种群中存在的位点移动的临时高比率。
