Mantri R R, Singh M, Radhakrishnan S, Sinna N
Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Int J Cardiol. 1994 Jun 1;45(1):69-75. doi: 10.1016/0167-5273(94)90055-8.
Thirty-three surgically proven cases of constrictive pericarditis were studied pre-operatively by echocardiography for left atrial dilatation and 18 of them underwent post-operative study at a mean follow-up period of 229 +/- 105 days. The degree of left atrial dilatation in these patients was compared with patients of restrictive cardiomyopathy (n = 8) and sex matched controls of similar age (n = 33). Significant left atrial dilatation was present in patients of constrictive pericarditis compared to controls and it was of a similar or greater degree compared to patients of restrictive cardiomyopathy (the left atrium to aorta ratio was 1.7 +/- 0.31, 1.53 +/- 0.18 and 1.07 +/- 0.1, in constrictive pericarditis, restrictive cardiomyopathy and controls, respectively, P = NS for constrictive pericarditis vs. restrictive cardiomyopathy and P < 0.001 for constrictive pericarditis vs. controls). There was no correlation of degree of left atrial dilatation with clinical and hemodynamic variables. Postoperatively, there was regression of left atrial size in patients with normal hemodynamics (n = 12, pre- vs. post-operative left atrium to aorta ratio 1.65 +/- 0.23 vs. 1.32 +/- 0.14, P < or = 0.001) and persisting or increasing left atrial dilatation in patients with persisting hemodynamic abnormality (n = 6, left atrium to aorta ratio 1.66 +/- 0.23 vs. 1.82 +/- 0.15, P = NS). We conclude that significant left atrial dilatation is a consistent echocardiographic feature of constrictive pericarditis. Hemodynamic normalization following successful pericardiectomy is associated with regression of atrial size.
对33例经手术证实的缩窄性心包炎患者进行术前超声心动图检查,以评估左心房扩张情况,其中18例患者在术后平均229±105天进行了随访研究。将这些患者的左心房扩张程度与限制性心肌病患者(n = 8)以及年龄和性别匹配的对照组(n = 33)进行比较。与对照组相比,缩窄性心包炎患者存在明显的左心房扩张,与限制性心肌病患者相比,其扩张程度相似或更大(缩窄性心包炎、限制性心肌病和对照组的左心房与主动脉比值分别为1.7±0.31、1.53±0.18和1.07±0.1,缩窄性心包炎与限制性心肌病相比P =无显著性差异,缩窄性心包炎与对照组相比P < 0.001)。左心房扩张程度与临床和血流动力学变量之间无相关性。术后,血流动力学正常的患者(n = 12,术前与术后左心房与主动脉比值分别为1.65±0.23和1.32±0.14,P≤0.001)左心房大小有所缩小,而血流动力学异常持续存在的患者(n = 6,左心房与主动脉比值为1.66±0.23和1.82±0.15,P =无显著性差异)左心房扩张持续或加重。我们得出结论,明显的左心房扩张是缩窄性心包炎一致的超声心动图特征。成功的心包切除术后血流动力学恢复正常与心房大小缩小相关。