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[幽门螺杆菌对甲硝唑耐药菌株的出现]

[Occurrence of Helicobacter pylori strains resistant to metronidazole].

作者信息

Andrzejewska E, Jenek J, Klincewicz H, Pietkiewicz K

机构信息

Zakład Mikrobiologii Lekarskiej i Klinika Gastroenterologii AM im. Karola Marcinkowskiego w Poznaniu.

出版信息

Med Dosw Mikrobiol. 1994;46(3):169-73.

PMID:7996934
Abstract

This study describes results of in vitro examination of susceptibility to metronidazole of clinical strains of Helicobacter pylori isolated from patients with gastritis. The susceptibility was determined by disc diffusion test. H. pylori was isolated from 44 (67.7%) of patients. Thirty six (81.8%) of the strains were resistant to metronidazole: 17 (85%) from 20 strains isolated from women and 19 (79.2%) from 24 strains isolated from men. This study emphasises the importance of monitoring the drug resistance of H. pylori during therapy.

摘要

本研究描述了从胃炎患者中分离出的幽门螺杆菌临床菌株对甲硝唑敏感性的体外检测结果。敏感性通过纸片扩散法测定。从44名(67.7%)患者中分离出幽门螺杆菌。36株(81.8%)菌株对甲硝唑耐药:从20名女性患者分离出的菌株中有17株(85%)耐药,从24名男性患者分离出的菌株中有19株(79.2%)耐药。本研究强调了在治疗期间监测幽门螺杆菌耐药性的重要性。

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[Occurrence of Helicobacter pylori strains resistant to metronidazole].[幽门螺杆菌对甲硝唑耐药菌株的出现]
Med Dosw Mikrobiol. 1994;46(3):169-73.
2
Susceptibility of Helicobacter pylori to metronidazole.幽门螺杆菌对甲硝唑的敏感性。
Am J Gastroenterol. 2003 Oct;98(10):2157-61. doi: 10.1111/j.1572-0241.2003.07681.x.
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Evaluation of Helicobacter pylori sensitivity to amoxycillin and metronidazole in dyspeptic patients.消化不良患者中幽门螺杆菌对阿莫西林和甲硝唑敏感性的评估。
Ital J Gastroenterol. 1993 Feb-Mar;25(2):65-7.
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[Study on metronidazole resistance to Helicobacter pylori from three populations with different ethnics in Yunnan].
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High percentage of clarithromycin and metronidazole resistance in Helicobacter pylori clinical isolates obtained from Spanish children.从西班牙儿童中分离出的幽门螺杆菌临床菌株对克拉霉素和甲硝唑的耐药率很高。
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Adding once-daily omeprazole 20 mg to metronidazole/amoxicillin treatment for Helicobacter pylori gastritis: a randomized, double-blind trial showing the importance of metronidazole resistance.在幽门螺杆菌胃炎的甲硝唑/阿莫西林治疗方案中加用每日一次的20毫克奥美拉唑:一项随机双盲试验表明甲硝唑耐药性的重要性。
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Eradication rates of Helicobacter pylori between metronidazole-sensitive and metronidazole-resistant strains with metronidazole containing regimen in Thai patients with peptic ulcer disease.在泰国消化性溃疡疾病患者中,含甲硝唑方案对甲硝唑敏感和耐药的幽门螺杆菌菌株的根除率。
J Med Assoc Thai. 2001 Jun;84 Suppl 1:S474-80.
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[In vitro antimicrobial susceptibility of Helicobacter pylori strains: isolation of strains resistant to clarithromycin].幽门螺杆菌菌株的体外抗菌药敏性:对克拉霉素耐药菌株的分离
Rev Med Chil. 2001 Jun;129(6):643-6.
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One-week ranitidine bismuth citrate versus colloidal bismuth subcitrate-based anti-Helicobacter triple therapy: a prospective randomized controlled trial.枸橼酸雷尼替丁铋与基于枸橼酸铋钾的抗幽门螺杆菌三联疗法一周对比:一项前瞻性随机对照试验
Am J Gastroenterol. 1999 Mar;94(3):721-4. doi: 10.1111/j.1572-0241.1999.00942.x.

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Drug Saf. 1996 Jul;15(1):30-52. doi: 10.2165/00002018-199615010-00003.