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[幽门螺杆菌对甲硝唑耐药菌株的出现]

[Occurrence of Helicobacter pylori strains resistant to metronidazole].

作者信息

Andrzejewska E, Jenek J, Klincewicz H, Pietkiewicz K

机构信息

Zakład Mikrobiologii Lekarskiej i Klinika Gastroenterologii AM im. Karola Marcinkowskiego w Poznaniu.

出版信息

Med Dosw Mikrobiol. 1994;46(3):169-73.

PMID:7996934
Abstract

This study describes results of in vitro examination of susceptibility to metronidazole of clinical strains of Helicobacter pylori isolated from patients with gastritis. The susceptibility was determined by disc diffusion test. H. pylori was isolated from 44 (67.7%) of patients. Thirty six (81.8%) of the strains were resistant to metronidazole: 17 (85%) from 20 strains isolated from women and 19 (79.2%) from 24 strains isolated from men. This study emphasises the importance of monitoring the drug resistance of H. pylori during therapy.

摘要

本研究描述了从胃炎患者中分离出的幽门螺杆菌临床菌株对甲硝唑敏感性的体外检测结果。敏感性通过纸片扩散法测定。从44名(67.7%)患者中分离出幽门螺杆菌。36株(81.8%)菌株对甲硝唑耐药:从20名女性患者分离出的菌株中有17株(85%)耐药,从24名男性患者分离出的菌株中有19株(79.2%)耐药。本研究强调了在治疗期间监测幽门螺杆菌耐药性的重要性。

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