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血型与疟疾

Blood groups and malaria.

作者信息

Montoya F, Restrepo M, Montoya A E, Rojas W

机构信息

Corporación para investigaciones Biológicas C.I.B. Medellín, Colombia.

出版信息

Rev Inst Med Trop Sao Paulo. 1994 Jan-Feb;36(1):33-8. doi: 10.1590/s0036-46651994000100006.

DOI:10.1590/s0036-46651994000100006
PMID:7997771
Abstract

The possible relationship between erythrocyte antigens and the presence of malaria infection by P. vivax and P. falciparum was sought in four different ethnic groups of two departments of Colombia. Malaria infection by P. falciparum was found in 91.4% of malaria infected blacks. No significant differences were found between the presence of malaria infection and ABO antigens. In the other blood groups, it was observed that groups MNSs conferred black people a greater Rr for malaria by both species of Plasmodium and that Duffy-negative blacks and indians appeared to be resistant to P. vivax infection. A predominance of P. vivax infection was observed in Katio Indians while P. falciparum was predominant in Kuna Indians; the reason for this finding still needs to be explored.

摘要

在哥伦比亚两个省的四个不同种族群体中,研究了红细胞抗原与间日疟原虫和恶性疟原虫疟疾感染存在之间的可能关系。在91.4%的感染疟疾的黑人中发现了恶性疟原虫感染。疟疾感染的存在与ABO抗原之间未发现显著差异。在其他血型中,观察到MNSs血型使黑人感染两种疟原虫的相对风险更高,并且达菲阴性的黑人和印第安人似乎对间日疟原虫感染具有抗性。在卡蒂奥印第安人中观察到间日疟原虫感染占优势,而在库纳印第安人中恶性疟原虫占优势;这一发现的原因仍有待探索。

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