Lipton R I
Alcohol Research Group, Berkeley, Calif.
Am J Public Health. 1994 Dec;84(12):1913-7. doi: 10.2105/ajph.84.12.1913.
The purpose of the study was to determine whether moderate alcohol use mediates or buffers the effect of stress on depression in a group of non-Hispanic White men and women.
Data are from the Los Angeles Epidemiological Catchment Area cohort. Individuals were assessed at two time periods, 1 year apart. Mean depression scores were analyzed for each level of stress and alcohol use.
In the simultaneous presence of both chronic strain and negative life events, a U-shaped pattern was observed in which abstainers and light and heavy drinkers had higher depression scores at the second time period than did light-moderate and moderate alcohol users. The U-shaped relationship remained when the effects of sex, age, and physical health status were controlled.
Light-moderate and moderate drinkers had less depression in the presence of stress than persons in other more extreme drinking categories. Moderate alcohol use may serve as a proxy for a spectrum of generally moderate behaviors that either attenuate the effect of stress on depression or suppress the effects of stress.
本研究旨在确定适量饮酒是否介导或缓冲压力对一组非西班牙裔白人男性和女性抑郁的影响。
数据来自洛杉矶流行病学集水区队列。个体在相隔1年的两个时间段接受评估。分析了每个压力水平和饮酒量下的平均抑郁得分。
在同时存在慢性压力和负面生活事件的情况下,观察到一种U形模式,即戒酒者、少量饮酒者和大量饮酒者在第二个时间段的抑郁得分高于轻度适量饮酒者和适量饮酒者。在控制了性别、年龄和身体健康状况的影响后,U形关系依然存在。
在有压力的情况下,轻度适量饮酒者和适量饮酒者比其他饮酒类别更极端的人抑郁程度更低。适量饮酒可能代表了一系列通常较为适度的行为,这些行为要么减轻压力对抑郁的影响,要么抑制压力的作用。