醛霉素，一种来自链霉菌的新型抗微生物抗生素。I. 分类学、发酵、分离、物理化学和生物学特性。
Aldecalmycin, a new antimicrobial antibiotic from Streptomyces. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.
作者信息
Sawa R, Takahashi Y, Itoh S, Shimanaka K, Kinoshita N, Homma Y, Hamada M, Sawa T, Naganawa H, Takeuchi T
机构信息
Institute of Microbial Chemistry, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1994 Nov;47(11):1266-72. doi: 10.7164/antibiotics.47.1266.
A new antibiotic, aldecalmycin, has been discovered in the culture broth of Streptomyces sp. MJ147-72F6. Aldecalmycin was purified by solvent extraction, Diaion HP-20 chromatography, silica gel chromatography, Sephadex LH-20 chromatography, HPLC and centrifugal partition chromatography. The 1H and 13C NMR spectra of aldecalmycin showed the presence of keto-enol tautomers. Aldecalmycin is equipotent in inhibiting the growth of sensitive and methicillin-resistant Staphylococcus aureus (MRSA).
一种新的抗生素——醛霉素，已在链霉菌属MJ147 - 72F6的培养液中被发现。醛霉素通过溶剂萃取、Diaion HP - 20柱色谱法、硅胶柱色谱法、葡聚糖凝胶LH - 20柱色谱法、高效液相色谱法和离心分配色谱法进行纯化。醛霉素的1H和13C核磁共振谱显示存在酮 - 烯醇互变异构体。醛霉素在抑制敏感和耐甲氧西林金黄色葡萄球菌（MRSA）生长方面具有同等效力。
Zotero 插件