Plantin P, Le Berre A, Le Roux P, Leroy J P
Service de Dermatologie, Hôpital Laennec, Quimper.
Arch Fr Pediatr. 1993 Aug-Sep;50(7):607-8.
Hyperpigmentation can be due to different cause or have no apparent cause.
A 4 year-old boy was examined because pigmentation had appeared 5 months earlier. The cutaneous lesions were blue-grey, macular (diameter: 2-3 cm), with a predilection for the trunk, the lower part of the neck and the proximal part of the legs. There was no pruritus and the lesions did not urticate when rubbed. Histologically, there was epidermal acanthosis, moderate hyperkeratosis and dermal infiltration with numerous melanophages. The clinical lesions remained stable 6 months later.
The cutaneous manifestations and their course are similar to those of idiopathic macular pigmentation usually reported in adolescents. Ultramicroscopic findings have led some authors to classify it as lichen planus.
色素沉着可能由不同原因引起，也可能无明显原因。
一名4岁男孩因5个月前出现色素沉着前来检查。皮肤损害为蓝灰色、斑疹（直径2 - 3厘米），好发于躯干、颈部下部和腿部近端。无瘙痒，皮损摩擦时不起风团。组织学检查显示表皮棘层肥厚、中度角化过度以及真皮内有大量噬黑素细胞浸润。6个月后临床损害保持稳定。
皮肤表现及其病程与通常在青少年中报道的特发性斑状色素沉着相似。超微结构检查结果使一些作者将其归类为扁平苔藓。
