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高度减毒痘病毒在体外诱导中性粒细胞发生功能性启动。

Highly attenuated poxviruses induce functional priming of neutrophils in vitro.

作者信息

Förster R, Wolf G, Mayr A

机构信息

Institut für Medizinische Mikrobiologie, Infektions- und Seuchenmedizin, Ludwig-Maximilian-Universität München, Federal Republic of Germany.

出版信息

Arch Virol. 1994;136(1-2):219-26. doi: 10.1007/BF01538831.

DOI:10.1007/BF01538831
PMID:8002789
Abstract

Highly attenuated poxvirus samples were used to examine the influence of potential poxvirus expression vector systems on neutrophil function. Exposure to the viruses alters the number of membrane bound complement-and Fc gamma-receptors and led to functional priming of neutrophils to subsequent stimuli.

摘要

高度减毒的痘病毒样本用于检测潜在痘病毒表达载体系统对中性粒细胞功能的影响。接触这些病毒会改变膜结合补体和Fcγ受体的数量，并导致中性粒细胞对后续刺激的功能致敏。

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Induction of cytotoxic T lymphocytes by recombinant canarypox (ALVAC) and attenuated vaccinia (NYVAC) viruses expressing the HIV-1 envelope glycoprotein.表达HIV-1包膜糖蛋白的重组金丝雀痘病毒（ALVAC）和减毒痘苗病毒（NYVAC）诱导细胞毒性T淋巴细胞。
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