Wyrzykiewicz E, Prukała W, Kedzia B
Wydział Chemii, Uniwersytet im. Adama Mickiewicza, Poznań, Polska.
Farmaco. 1994 Feb;49(2):127-31.
The synthesis of 19 new N-substituted derivatives of (E)-alpha and gamma-azastillbenols-2'(3' and 4') and their antimicrobial activity are reported. In particular, compounds 4a-4f and 6a showed good antibacterial activity against Staphylococcus aureus, Streptococcus faecalis, Bacillus subtilis and Escherichia coli.
报道了19种新型(E)-α和γ-氮杂二苯乙烯醇-2'(3'和4')的N-取代衍生物的合成及其抗菌活性。特别地,化合物4a - 4f和6a对金黄色葡萄球菌、粪肠球菌、枯草芽孢杆菌和大肠杆菌表现出良好的抗菌活性。