与肝线粒体DNA结合的低分子量肽对体外DNA复制的影响。
Effect of a low molecular weight peptide bound to liver mitochondrial DNA on in vitro DNA duplication.
作者信息
Spena A, Pedace V, Covello C, De Cicco T, Mazzulla S, Martino G
机构信息
Department of Cell Biology, University of Calabria, Rende, CS.
出版信息
Boll Soc Ital Biol Sper. 1993 Dec;69(12):755-9.
PMID:8003290
Abstract
Authors tested "in vitro" action of a low molecular weight peptide fraction extracted by mitochondrial DNA from calf liver. The fraction acts upon duplication performed by E. Coli DNA polymerase I on poli dAT dAT template inhibiting chain elongation. The authors hypothesize that a similar role is exerted by this fraction "in vitro" on mitochondrial DNA template.
摘要
作者测试了从小牛肝脏线粒体DNA中提取的低分子量肽组分的“体外”作用。该组分作用于大肠杆菌DNA聚合酶I在聚dAT dAT模板上进行的复制，抑制链延伸。作者推测该组分在“体外”对线粒体DNA模板发挥类似作用。
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