Guisantes A, Fraga A, Galimidi S, Mendez-Tula A, Brovetto-Cruz J
Reproduccion. 1976 Jan-Jun;3(1-2):135-9.
The action of HCS and HCG on cell-mediated immunity has been investigated. Full-thickness skin homografts were performed in 40 whole adult female Wistar rats. Brown rats of the A X C strain were selected as donors. The animals were divided into four groups injected with HCS, HCG, HCS + HCG, and saline. The graft rejection time and the wet and dry weight of thymus and spleen were evaluated. No hormonal treatment showed any effect on skin graft survival. Thymus weight, both wet and dry, decreased significantly by treatment with HCP or HCS + HCG. No modification was observed in spleen weight. These results do not agree with the theory that HCS and HCG modify immunological competence of maternal lymphocytes and thus may contribute to prevent rejection of the fetus.
已对人绒毛膜促生长素（HCS）和人绒毛膜促性腺激素（HCG）对细胞介导免疫的作用进行了研究。在40只成年雌性Wistar大鼠身上进行了全层皮肤同种移植。选用A×C品系的棕色大鼠作为供体。将动物分为四组，分别注射HCS、HCG、HCS + HCG和生理盐水。评估了移植排斥时间以及胸腺和脾脏的湿重与干重。未发现任何激素处理对皮肤移植存活有任何影响。经HCP或HCS + HCG处理后，胸腺的湿重和干重均显著降低。脾脏重量未观察到变化。这些结果与HCS和HCG改变母体淋巴细胞免疫能力从而可能有助于防止胎儿排斥的理论不一致。
