Pernitcheva-Rostaing E, Morin P
J Gynecol Obstet Biol Reprod (Paris). 1976;5(7):871-7.
The present work studies the effect of the placental hormones HCG and HCS on cellular immunity in vitro. These two hormones used in identical or greater concentrations than found in circulating blood inhibit lymphoblastic changes in mixed cultures of lymphocytes. It is possible that HCG and HCS have the same inhibiting effect in vivo on immunity by cellular mediation in the pregnant woman. This inhibition could be of the greatest importance at the surface of the trophoblast where their concentration is probably raised, and where contact between fetal antigens and maternal blood also takes place.
本研究探讨胎盘激素人绒毛膜促性腺激素（HCG）和人胎盘催乳素（HCS）对体外细胞免疫的影响。这两种激素在使用浓度等于或高于血液循环中的浓度时，可抑制淋巴细胞混合培养中的淋巴细胞转化。HCG和HCS在体内可能对孕妇细胞介导的免疫具有相同的抑制作用。这种抑制作用在滋养层表面可能最为重要，因为在那里它们的浓度可能升高，并且胎儿抗原与母体血液之间也会发生接触。
