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发育迟缓的可逆性:发展中国家儿童的流行病学研究结果

Reversibility of stunting: epidemiological findings in children from developing countries.

作者信息

Martorell R, Khan L K, Schroeder D G

机构信息

Centre for International Health, Emory University, School of Public Health, Atlanta, GA 30329.

出版信息

Eur J Clin Nutr. 1994 Feb;48 Suppl 1:S45-57.

PMID:8005090
Abstract

The growth literature from developing countries is reviewed to assess the extent to which stunting, a phenomenon of early childhood, can be reversed in later childhood and adolescence. The potential for catch-up growth increases as maturation is delayed and the growth period is prolonged. However, maturational delays in developing countries are usually less than two years, only enough to compensate for a small fraction of the growth retardation of early childhood. Follow-up studies find that subjects who remain in the setting in which they became stunted experience little or no catch-up in growth later in life. Improvements in living conditions, as through food supplementation or through adoption, trigger catch-up growth but do so more effectively in the very young. One study cautions that in older adopted subjects, accelerated growth may accelerate maturation, shorten the growth period and lead to short adult stature.

摘要

对来自发展中国家的增长文献进行了综述,以评估发育迟缓(一种幼儿期现象)在童年后期和青春期能够逆转的程度。随着成熟延迟和生长期延长,追赶生长的潜力会增加。然而,发展中国家的成熟延迟通常不到两年,仅足以弥补幼儿期生长迟缓的一小部分。随访研究发现,那些仍处于发育迟缓环境中的受试者在以后的生活中几乎没有或根本没有出现追赶生长。生活条件的改善,如通过食物补充或收养,会引发追赶生长,但对非常年幼的儿童效果更佳。一项研究警告说,对于年龄较大的被收养者,加速生长可能会加速成熟、缩短生长期并导致成年后身材矮小。

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