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卵巢子宫内膜样癌。17例临床病理研究。

Endometrioid carcinoma of the ovary. A clinicopathological study of 17 cases.

作者信息

Martín Jimenez A, Miralles Pi R M, Giné Martín L, Petit Cabello J, Balagueró Lladó L

机构信息

Servicio de Ginecología, Ciudad Sanitaria y Universitaria de Bellvitge.

出版信息

Eur J Gynaecol Oncol. 1994;15(2):96-100.

PMID:8005149
Abstract

Seventeen patients with endometrioid carcinoma of the ovary were studied in order to establish clinical, surgical and histological prognostic factors. Disease recurred in 7 cases (41%) and statistically correlation was found between presence of ascites above 200 ml, advanced stage of the disease, low level of cellular differentiation and peritoneal disease and/or a residual tumour after surgery. No correlation was found between age at presentation, menopausal status, size of tumour or bilaterality. The estimated survival rate for 5-years was placed between 40%-50%. Pathological study found associated endometrioid disease in 3 cases (20%) (2 adenocarcinomas, 1 hyperplasia with atypias), and ovarian endometriosis in 2 cases (12%). Furthermore, two extremely rare cases are reported: clinical presentation of paraneoplastic dermatomiositis and recurrence at the laparoscopic puncture site.

摘要

为了确定临床、手术和组织学预后因素,对17例卵巢子宫内膜样癌患者进行了研究。7例(41%)出现疾病复发,并且发现腹水超过200ml、疾病晚期、细胞分化程度低以及腹膜疾病和/或手术后残留肿瘤之间存在统计学相关性。未发现发病年龄、绝经状态、肿瘤大小或双侧性之间存在相关性。估计5年生存率在40%-50%之间。病理研究发现3例(20%)伴有子宫内膜样疾病(2例腺癌,1例非典型增生),2例(12%)伴有卵巢子宫内膜异位症。此外,还报告了两例极为罕见的病例:副肿瘤性皮肌炎的临床表现以及腹腔镜穿刺部位复发。

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