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抗病毒药物:现状与未来前景。

Antiviral drugs: present status and future prospects.

作者信息

van der Sijs I H, Wiltink E H

机构信息

Academic Medical Centre, Department of Pharmacy, Amsterdam, The Netherlands.

出版信息

Int J Biochem. 1994 May;26(5):621-30. doi: 10.1016/0020-711x(94)90161-9.

Abstract
  1. There is a limited number of antiviral drugs available for therapy. Many investigations and new analytical techniques have unraveled the development and progression of a viral infection. Nowadays there is a good understanding of the multiplication cycle of viruses, including the human immunodeficiency virus. 2. In this article the currently available antiviral drugs are presented arranged by their mode of action that can be understood by the multiplication cycle of the virus. 3. Clinical use and side-effects are discussed as well as place in current therapy. Some attention is paid on promising investigational antivirals.
摘要
  1. 可用于治疗的抗病毒药物数量有限。许多研究和新的分析技术揭示了病毒感染的发展和进程。如今,人们对病毒的增殖周期,包括人类免疫缺陷病毒的增殖周期有了很好的了解。2. 在本文中,目前可用的抗病毒药物按照其作用方式进行介绍,这些作用方式可以通过病毒的增殖周期来理解。3. 讨论了临床应用、副作用以及在当前治疗中的地位。还对有前景的研究性抗病毒药物给予了一些关注。

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