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支气管败血波氏杆菌的上皮细胞侵袭与存活

Epithelial cell invasion and survival of Bordetella bronchiseptica.

作者信息

Schipper H, Krohne G F, Gross R

机构信息

Lehrstuhl für Mikrobiologie, Biozentrum, Universität Würzburg, Germany.

出版信息

Infect Immun. 1994 Jul;62(7):3008-11. doi: 10.1128/iai.62.7.3008-3011.1994.

DOI:10.1128/iai.62.7.3008-3011.1994
PMID:8005690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC302913/
Abstract

Wild-type Bordetella bronchiseptica and a bvg mutant strain were used for invasion and survival experiments in human Caco-2 and A549 epithelial cells. Both bacterial strains were able to enter and persist within the host cells for at least a week. A significant proportion of the bacteria from both B. bronchiseptica strains but not from Bordetella pertussis were found free in the cytoplasm, suggesting different invasion and survival strategies of the two species in epithelial cells.

摘要

野生型支气管败血波氏杆菌和一个bvg突变株用于在人Caco-2和A549上皮细胞中的侵袭和存活实验。两种菌株都能够进入宿主细胞并在其中持续存在至少一周。发现来自两种支气管败血波氏杆菌菌株而非百日咳博德特氏菌的很大一部分细菌游离于细胞质中，这表明这两个菌种在上皮细胞中有不同的侵袭和存活策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbb8/302913/6f71be0db470/iai00007-0368-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbb8/302913/6f71be0db470/iai00007-0368-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbb8/302913/6f71be0db470/iai00007-0368-a.jpg

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本文引用的文献

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Growth of Bordetella pertussis in tissue culture.百日咳博德特氏菌在组织培养中的生长
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