Krasa N R, Tolbert H A
Department of Psychiatry, Ohio State University, Columbus 43210.
J Affect Disord. 1994 Mar;30(3):175-84. doi: 10.1016/0165-0327(94)90078-7.
The clinical records of 53 adolescent inpatients diagnosed with bipolar disorder were re-evaluated to examine their profiles and differential diagnoses. Seventy-two percent satisfied DSM-III-R Bipolar Disorder criteria and most presented with manic or mixed mood symptoms. Half were psychotic. Non-affective psychosis, unipolar depression, organic syndromes and disruptive behavioral disorders complicated the differential diagnoses, particularly among younger boys. The well-documented bipolars were characterized by affective symptoms prior to the first admission and shorter hospitalizations than the remaining subjects. A recent trend towards overdiagnosis of bipolar disorder is suggested in some patients.
对53名被诊断为双相情感障碍的青少年住院患者的临床记录进行了重新评估,以检查他们的病情概况和鉴别诊断。72%的患者符合《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)双相情感障碍标准,大多数患者表现为躁狂或混合情绪症状。半数患者有精神病性症状。非情感性精神病、单相抑郁症、器质性综合征和破坏性行为障碍使鉴别诊断变得复杂,尤其是在年龄较小的男孩中。有充分记录的双相情感障碍患者的特点是首次入院前有情感症状,且住院时间比其他患者短。在一些患者中提示了近期双相情感障碍过度诊断的趋势。