Tarlo S M, Sussman G, Contala A, Swanson M C
Department of Medicine, University of Toronto, Ontario, Canada.
J Allergy Clin Immunol. 1994 Jun;93(6):985-9. doi: 10.1016/s0091-6749(94)70045-1.
Our objective was to assess airborne latex allergen exposure in the workplace of a hospital laboratory technician with occupational latex sensitization and repeated anaphylactic episodes from this. Her allergic manifestations had cleared only when coworkers changed to powder-free latex gloves. Therefore a laboratory still using powdered latex gloves was selected for comparative airborne latex sampling.
The design was a survey.
We used a hospital hematology laboratory, and a biochemistry laboratory was used for comparison.
The index case with latex allergy is described. An average of 10 employees worked on the day shift in the same laboratory, and 10 employees worked in the biochemistry laboratory studied.
Airborne latex allergen levels obtained by high airflow area sampling were compared in the laboratory using powder-free latex gloves and in the laboratory using powdered latex gloves.
Levels were below the level of detection (< 0.02 ng/m3 of latex allergen) in the laboratory using powder-free latex gloves but ranged from 39 to 311 ng/m3 in the laboratory using powdered gloves.
Airborne latex allergen is produced with use of powdered latex gloves. Such usage by coworkers may provoke respiratory and anaphylactic response to latex in sensitized subjects. Use of powder-free gloves by coworkers may enable such patients to continue work in their trained profession and may prevent measurable airborne latex exposure. Affected patients, however, still need to avoid direct latex contact.
我们的目的是评估一名医院实验室技术员工作场所的空气传播乳胶过敏原暴露情况,该技术员有职业性乳胶致敏并因此出现反复过敏反应。只有当同事更换为无粉乳胶手套时,她的过敏症状才得以缓解。因此,选择了一个仍在使用含粉乳胶手套的实验室进行空气传播乳胶采样对比。
采用调查设计。
我们使用了一家医院的血液学实验室,并以一个生物化学实验室作为对照。
描述了乳胶过敏的索引病例。在同一实验室,日班平均有10名员工工作,在被研究的生物化学实验室也有10名员工工作。
比较使用无粉乳胶手套的实验室和使用含粉乳胶手套的实验室通过高气流区域采样获得的空气传播乳胶过敏原水平。
在使用无粉乳胶手套的实验室中,乳胶过敏原水平低于检测限(<0.02 ng/m³乳胶过敏原),但在使用含粉乳胶手套的实验室中,水平范围为39至311 ng/m³。
使用含粉乳胶手套会产生空气传播乳胶过敏原。同事的这种使用方式可能会引发致敏个体对乳胶的呼吸道和过敏反应。同事使用无粉手套可能使此类患者能够继续从事其专业工作,并可防止可测量的空气传播乳胶暴露。然而,受影响的患者仍需避免直接接触乳胶。