Muramatsu N, Shiga K, Kondo T
Faculty of Pharmaceutical Sciences, Science University of Tokyo, Japan.
J Microencapsul. 1994 Mar-Apr;11(2):171-8. doi: 10.3109/02652049409040448.
A novel emulsification technique which employs microporous glass membranes was adopted to prepare polyamide microcapsules of narrow size distribution. This technique proved to be simple and quite efficient for getting fairly uniform sizes of dispersed liquid droplets. Polyamide microcapsules prepared by using this technique were found not completely monodisperse, but far more satisfactory than those by any conventional mechanical methods in view of their narrow size distribution. This method also seems promising to get various sizes of the capsules by selecting the pore size of the glass membranes.
采用一种利用微孔玻璃膜的新型乳化技术制备了尺寸分布窄的聚酰胺微胶囊。事实证明，该技术简单且高效，能获得相当均匀尺寸的分散液滴。用这种技术制备的聚酰胺微胶囊并非完全单分散，但鉴于其窄尺寸分布，比任何传统机械方法制备的微胶囊都要令人满意得多。通过选择玻璃膜的孔径，这种方法似乎也有希望获得各种尺寸的胶囊。
