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Ischemia-selectivity: a new concept of cardioprotection by calcium antagonists.

作者信息

Heusch G

出版信息

Basic Res Cardiol. 1994 Jan-Feb;89(1):2-5. doi: 10.1007/BF00788672.

DOI:10.1007/BF00788672
PMID:8010932
Abstract
摘要

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Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.低剂量钙拮抗剂可降低离体心脏在缺血和再灌注期间的能量需求及细胞损伤。
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Combination drug therapy with calcium-channel blockers in the treatment of systemic hypertension.钙通道阻滞剂联合药物治疗系统性高血压。
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The physiology of cardiac calcium handling.心脏钙处理的生理学
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本文引用的文献

1
Impact of alpha-adrenergic coronary vasoconstriction on the transmural myocardial blood flow distribution during humoral and neuronal adrenergic activation.α-肾上腺素能冠状动脉收缩对体液和神经肾上腺素能激活期间跨壁心肌血流分布的影响。
Circ Res. 1993 Nov;73(5):869-86. doi: 10.1161/01.res.73.5.869.
2
A proischaemic action of nisoldipine: relationship to a decrease in perfusion pressure and comparison to dipyridamole.尼索地平的缺血前作用:与灌注压降低的关系及与双嘧达莫的比较。
Cardiovasc Res. 1993 Jul;27(7):1254-9. doi: 10.1093/cvr/27.7.1254.
3
The role of heart rate in myocardial ischemia and infarction: implications of myocardial perfusion-contraction matching.
心率在心肌缺血和梗死中的作用:心肌灌注-收缩匹配的意义。
Prog Cardiovasc Dis. 1993 Jul-Aug;36(1):61-74. doi: 10.1016/0033-0620(93)90022-6.
4
[The concept of "dynamic" coronary artery stenosis].["动态"冠状动脉狭窄的概念]
Z Kardiol. 1982 Jul;71(7):439-44.
5
The effects of cardiac sympathetic nerve stimulation on perfusion of stenotic coronary arteries in the dog.心脏交感神经刺激对犬狭窄冠状动脉灌注的影响。
Circ Res. 1983 Jul;53(1):8-15. doi: 10.1161/01.res.53.1.8.
6
Coronary artery spasm: demonstration, definition, diagnosis, and consequences.冠状动脉痉挛:表现、定义、诊断及后果
Prog Cardiovasc Dis. 1982 Nov-Dec;25(3):169-92. doi: 10.1016/0033-0620(82)90015-9.
7
Nifedipine prevents sympathetic vasoconstriction distal to severe coronary stenoses.硝苯地平可预防严重冠状动脉狭窄远端的交感神经血管收缩。
J Cardiovasc Pharmacol. 1984 May-Jun;6(3):378-83. doi: 10.1097/00005344-198405000-00002.
8
Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.尼群地平对心脏钙通道的阻断作用:与失活状态的高亲和力结合。
Proc Natl Acad Sci U S A. 1984 Oct;81(20):6388-92. doi: 10.1073/pnas.81.20.6388.
9
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.二氢吡啶类钙通道拮抗剂对小牛心脏浦肯野纤维钙通道电流的电压依赖性阻滞作用。
Circ Res. 1984 Sep;55(3):336-48. doi: 10.1161/01.res.55.3.336.
10
Attenuation of exercise-induced myocardial ischemia in dogs with recruitment of coronary vasodilator reserve by nifedipine.
Circulation. 1987 Feb;75(2):482-90. doi: 10.1161/01.cir.75.2.482.