1990年加尔各答登革出血热疫情
Dengue haemorrhagic fever (DHF) outbreak in Calcutta--1990.
作者信息
Bhattacharjee N, Mukherjee K K, Chakravarti S K, Mukherjee M K, De P N, Sengupta M, Banik G B, Bhowmick P, Sinha S K, Chakraborty M S
机构信息
Department of Virology, STM, Calcutta, India.
出版信息
J Commun Dis. 1993 Mar;25(1):10-4.
An outbreak of Dengue Haemorrhagic Fever (DHF) occurred in Calcutta between September and December, 1990. Children and young adults were the major victims. Haemorrhagic manifestations and shocks were the main features in most of the hospitalised cases. Five mouse pathogenic agents were isolated from 105 acute cases and all were identified as DEN-3. HI and CF test with 55 paired sera revealed evidence of dengue infection in 33 (60 per cent) and flavivirus group reaction including dengue in 17 (30.9 per cent). It was for the first time, that DEN-3 was considered to be the etiologic agent for DHF in Calcutta.
1990年9月至12月期间，加尔各答爆发了登革出血热（DHF）。儿童和年轻人是主要受害者。大多数住院病例的主要特征是出血表现和休克。从105例急性病例中分离出5种鼠病原体，均被鉴定为DEN-3。对55对配对血清进行的血凝抑制试验（HI）和补体结合试验（CF）显示，33例（60%）有登革热感染证据，17例（30.9%）有包括登革热在内的黄病毒属群反应。这是首次认为DEN-3是加尔各答登革出血热的病原体。
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