De Craemer D, Roels F
Department of Human Anatomy and Embryology, Vrije Universiteit Brussel, Belgium.
J Hepatol. 1994 Mar;20(3):394-7. doi: 10.1016/s0168-8278(94)80014-6.
In a patient with nodular regenerative hyperplasia of the liver, peroxisomes formed rows along the sinusoidal surface of the parenchymal cells, in contrast to their homogeneous distribution in the normal liver. In some cells, peroxisomes had a perinuclear configuration. Morphometric data were compared to those of seven control livers and revealed normal values of the peroxisomal diameter, axial ratio, volume density, numerical density and surface density. Peroxisomes with cytoplasmic invaginations, protrusions and gastruloid cisternae were rare. Angular profiles were frequently found. The peculiar distribution of the peroxisomes may be linked to the deficient blood supply to the liver in nodular regenerative hyperplasia.
在一名患有肝脏结节性再生性增生的患者中，过氧化物酶体沿着实质细胞的窦状表面形成排，这与它们在正常肝脏中的均匀分布形成对比。在一些细胞中，过氧化物酶体呈核周构型。将形态计量学数据与七个对照肝脏的数据进行比较，结果显示过氧化物酶体的直径、轴比、体积密度、数量密度和表面密度值均正常。具有胞质内陷、突起和原肠胚样池的过氧化物酶体很少见。经常发现角状轮廓。过氧化物酶体的特殊分布可能与结节性再生性增生中肝脏血液供应不足有关。
