Preusser B A, Winningham M L, Clanton T L
College of Nursing, Ohio State University, Columbus.
Chest. 1994 Jul;106(1):110-7. doi: 10.1378/chest.106.1.110.
This study determined the effect of a high vs low resistive inspiratory muscle interval training protocol on inspiratory muscle strength (PImax), incremental inspiratory threshold loading (Pitl), inspiratory muscle endurance (IE), and 12-minute distance test (12 MD) in severely impaired patients with COPD. We used a double-blind, two-group, repeated-measure design. Group 1 (n = 12) received supervised high resistive loading at approximately 52 percent PImax and group 2 (n = 8) received supervised low resistive loading at approximately 22 percent PImax. All subjects trained three times weekly (progressing from 5 min per session in week 1 to 18 min per session in week 12) for 12 weeks. After three practice sessions, measures of PImax, Pitl, IE, and 12 MD were taken at baseline, at 4-week intervals, and within 72 h of completing the protocol. Group 1 showed significant improvement in all four dependent variables while group 2 improved in Pitl, IE, and 12 MD. The results suggest there is no significant difference between high and low resistive interval training in more severely impaired patients with COPD.
本研究确定了高阻力与低阻力吸气肌间歇训练方案对重度慢性阻塞性肺疾病（COPD）患者吸气肌力量（最大吸气压，PImax）、递增吸气阈值负荷（Pitl）、吸气肌耐力（IE）和12分钟步行距离测试（12 MD）的影响。我们采用了双盲、两组、重复测量设计。第1组（n = 12）接受约为PImax 52%的监督下的高阻力负荷训练，第2组（n = 8）接受约为PImax 22%的监督下的低阻力负荷训练。所有受试者每周训练3次（从第1周的每次训练5分钟逐渐增加到第12周的每次训练18分钟），共训练12周。在3次练习课后，在基线、每隔4周以及完成训练方案后的72小时内测量PImax、Pitl、IE和12 MD。第1组在所有四个因变量上均有显著改善，而第2组在Pitl、IE和12 MD方面有所改善。结果表明，在病情更严重的COPD患者中，高阻力与低阻力间歇训练之间没有显著差异。
