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新世界的基因变异:古代牙齿、骨骼和组织作为DNA的来源。

Genetic variation in the New World: ancient teeth, bone, and tissue as sources of DNA.

作者信息

Merriwether D A, Rothhammer F, Ferrell R E

机构信息

Department of Human Genetics, University of Pittsburgh, Pennsylvania 15108.

出版信息

Experientia. 1994 Jun 15;50(6):592-601. doi: 10.1007/BF01921730.

Abstract

Examination of ancient and contemporary Native American mtDNA variation via diagnostic restriction sites and the 9-bp Region V deletion suggests a single wave of migration into the New World. This is in contrast to data from Torroni et al. which suggested two waves of migration into the New World (the NaDene and Amerind). All four founding lineage types are present in populations in North, Central, and South America suggesting that all four lineages came over together and spread throughout the New World. Ancient Native American DNA shows that all four lineages were present before European contact in North America, and at least two were present in South America. The presence of all four lineages in the NaDene and the Amerinds argues against separate migrations founding these two groups, although admixture between the groups is still a viable explanation for the presence of all four types in the NaDene.

摘要

通过诊断性限制性酶切位点和9碱基对的V区缺失来检测古代和当代美洲原住民线粒体DNA的变异,结果表明进入新大陆的移民是一波完成的。这与托罗尼等人的数据形成对比,他们的数据表明进入新大陆的移民有两波(纳-德内人和美洲印第安人)。所有四种奠基谱系类型都存在于北美洲、中美洲和南美洲的人群中,这表明所有四种谱系是一起到来并在新大陆传播开来的。古代美洲原住民的DNA显示,在欧洲人接触北美洲之前,所有四种谱系就已存在,并且至少有两种存在于南美洲。在纳-德内人和美洲印第安人中都存在所有四种谱系,这反驳了这两个群体是由不同移民建立的观点,尽管群体之间的混合仍然是纳-德内人存在所有四种类型的一个合理的解释。

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