住院患者的致命性肺栓塞：冬季高峰的证据。

Fatal pulmonary embolism in hospitalized patients: evidence for a winter peak.

作者信息

Manfredini R, Gallerani M, Salmi R, Zamboni P, Fersini C

机构信息

Institute of Internal Medicine, University of Ferrara Medical School, Italy.

出版信息

J Int Med Res. 1994 Mar-Apr;22(2):85-9. doi: 10.1177/030006059402200203.

DOI:10.1177/030006059402200203

PMID:8020642

Abstract

This study was intended to determine whether there are circa-annual variations in the incidence of fatal pulmonary embolism for hospitalized patients. Patients (152), admitted into both the medical and surgical departments of St. Anna Hospital of Ferrara, Italy, during an 8-year period (1983-1990) and who died in hospital as a result of pulmonary embolism, were considered. The day and month of death were registered, and analysed by inferential statistics (single cosinor). A circa-annual variation, with a statistically significant peak in late January (P = 0.002), was found for the total sample. After stratification by sex, this winter peak was confirmed only for women (P = 0.006).

摘要

本研究旨在确定住院患者致命性肺栓塞的发病率是否存在近似年度的变化。研究纳入了1983年至1990年这8年期间在意大利费拉拉圣安娜医院内科和外科住院、并因肺栓塞在医院死亡的患者（共152例）。记录了死亡日期和月份，并采用推断统计学方法（单余弦分析）进行分析。在整个样本中发现了近似年度的变化，1月下旬有一个具有统计学意义的峰值（P = 0.002）。按性别分层后，仅女性存在冬季峰值（P = 0.006）。