Oclarit J M, Okada H, Ohta S, Kaminura K, Yamaoka Y, Iizuka T, Miyashiro S, Ikegami S
Department of Applied Biochemistry, Hiroshima University, Japan.
Microbios. 1994;78(314):7-16.
The bacterial isolate, M22-1, belonging to the genus Vibrio was obtained from an homogenate of the sponge, Hyatella sp. The bacterium was cultured in marine agar and was found to produce an anti-Bacillus compound. The substance was chemically identified as a peptide antibiotic, an andrimid. The same substance was found in the sponge extract, suggesting that the active component was synthesized by the associated microorganism.
从海绵Hyatella sp.的匀浆中分离出属于弧菌属的细菌菌株M22-1。该细菌在海洋琼脂中培养，发现能产生一种抗芽孢杆菌化合物。该物质经化学鉴定为一种肽抗生素——安曲霉素。在海绵提取物中也发现了相同的物质，这表明活性成分是由相关微生物合成的。
