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海洋天然产物。三十四。三吲哚啉，一种新的抗生素吲哚三聚体，由从海洋海绵高枝软海绵分离出的弧菌属细菌产生。

Marine natural products. XXXIV. Trisindoline, a new antibiotic indole trimer, produced by a bacterium of Vibrio sp. separated from the marine sponge Hyrtios altum.

作者信息

Kobayashi M, Aoki S, Gato K, Matsunami K, Kurosu M, Kitagawa I

机构信息

Faculty of Pharmaceutical Sciences, Osaka University, Japan.

出版信息

Chem Pharm Bull (Tokyo). 1994 Dec;42(12):2449-51. doi: 10.1248/cpb.42.2449.

DOI:10.1248/cpb.42.2449
PMID:7697760
Abstract

A new antibiotic indole trimer named trisindoline (1) was isolated, together with a known dioxopiperazine brevianamide F (2), from the culture of a bacterium of Vibrio sp., which was separated from the Okinawan marine sponge Hyrtios altum. The structure of trisindoline (1) has been determined on the bases of physicochemical evidence and chemical synthesis.

摘要

从冲绳海洋海绵Hyrtios altum分离出的弧菌属细菌培养物中，分离出一种名为三吲哚啉（1）的新型抗生素吲哚三聚体，以及一种已知的二氧代哌嗪短杆菌肽F（2）。已根据物理化学证据和化学合成确定了三吲哚啉（1）的结构。

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