Sato N, Miyajima A
DNAX Research Institute of Molecular and Cellular Biology, Palo Alto.
Curr Opin Cell Biol. 1994 Apr;6(2):174-9. doi: 10.1016/0955-0674(94)90133-3.
The class I cytokine receptors consist of multiple subunits without any intrinsic enzymatic activities. Receptors for a subset of cytokines with overlapping biological activities often share a common receptor subunit with a signaling function. Each receptor regulates its specific signaling pathways, as well as common pathways depending on the target cell type.
I类细胞因子受体由多个亚基组成，没有任何内在的酶活性。具有重叠生物学活性的一部分细胞因子的受体通常共享一个具有信号传导功能的共同受体亚基。每个受体根据靶细胞类型调节其特定的信号通路以及共同通路。
