Kikuchi R, Watabe N, Konno T, Mishina N, Sekizawa K, Sasaki H
NTT Tohoku Hospital, Tohoku University School of Medicine, Sendai, Japan.
Am J Respir Crit Care Med. 1994 Jul;150(1):251-3. doi: 10.1164/ajrccm.150.1.8025758.
Pneumonia is a major cause of death in the elderly. To investigate the role of silent aspiration in community-acquired pneumonia, we examined the occurrence of silent aspiration during sleep in 14 elderly patients with acute episode of pneumonia and 10 age-matched control subjects by a new technique using indium111 chloride. Scanning of the thorax demonstrated that 71% of patients aspirated, whereas aspiration was observed in only 10% of control subjects. The percentage of positive scans was significantly higher in patients with acute episode of pneumonia than in control subjects (p < 0.02). The results may indicate an important role of silent aspiration in the development of community-acquired pneumonia in the elderly.
肺炎是老年人死亡的主要原因。为了研究隐性误吸在社区获得性肺炎中的作用，我们采用一种使用氯化铟111的新技术，检查了14例患有急性肺炎发作的老年患者和10例年龄匹配的对照受试者在睡眠期间隐性误吸的发生情况。胸部扫描显示，71%的患者发生了误吸，而对照受试者中只有10%观察到误吸。急性肺炎发作患者的扫描阳性率显著高于对照受试者（p < 0.02）。结果可能表明隐性误吸在老年人社区获得性肺炎的发生中起重要作用。
