Yamaguchi H, Kajita M
Department of Ophthalmology, Fukushima Medical College, Japan.
Nippon Ganka Gakkai Zasshi. 1994 Jun;98(6):566-74.
We analyzed corneal endothelial cells in 1,026 eyes from 12 to 29-year-old patients who had no eye disease except refractive error. Morphometric parameters were examined for their distribution and correlation with refractive elements. The distribution of cell density and hexagonal cells in percentage was normal. The logarithmic value of mean cell area and coefficient of variation (CV) also had normal distribution. There was also significant correlation between aging and morphometric parameters, i.e., positive correlation between the mean cell area and the CV, and negative correlation between the cell density and the hexagonality. There was significant correlation between corneal refraction and morphometric parameters, i.e., negative correlation with mean cell area, and positive correlation with cell density. There was also significant negative correlation between the corneal astigmatism and the hexagonality. Consequently, we suggest that the distribution of each morphometric parameter and the difference in age and refractive elements should be considered when discussing morphometry of the corneal endothelial cells.
我们分析了12至29岁、除屈光不正外无其他眼部疾病患者的1026只眼睛的角膜内皮细胞。检查形态计量学参数的分布及其与屈光成分的相关性。细胞密度和六边形细胞百分比的分布正常。平均细胞面积的对数值和变异系数（CV）也呈正态分布。年龄与形态计量学参数之间也存在显著相关性，即平均细胞面积与CV呈正相关，细胞密度与六边形度呈负相关。角膜屈光与形态计量学参数之间存在显著相关性，即与平均细胞面积呈负相关，与细胞密度呈正相关。角膜散光与六边形度之间也存在显著负相关。因此，我们建议在讨论角膜内皮细胞形态学时，应考虑每个形态计量学参数的分布以及年龄和屈光成分的差异。
