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腹部结肠切除术为大量下消化道出血提供了安全的治疗方法。

Abdominal colectomy offers safe management for massive lower GI bleed.

作者信息

Baker R, Senagore A

机构信息

St. Mary's Hospital, Grand Rapids, Michigan.

出版信息

Am Surg. 1994 Aug;60(8):578-81; discussion 582.

PMID:8030811
Abstract

Preoperative localization of lower gastrointestinal (LGI) bleeding has been advocated on the presumption that lower morbidity and mortality are associated with limited colonic resection versus abdominal colectomy. However, extensive preoperative evaluation, especially when negative, may unnecessarily delay surgical therapy in the actively hemorrhaging patient. The purpose of this study was to analyze the mortality and morbidity associated with total abdominal colectomy (TAC) versus limited colonic resection (LIM), when performed for massive LGI hemorrhage. Sixty-one patients admitted for massive LGI bleeding (> or = 1 unit packed red blood cells (PRBCs) transfused preoperatively) over a 5-year period were analyzed. The following data was collected: preop PRBCs; total PRBCs; Apache score; age; resection type (LIM [n = 42] versus TAC [n = 19]); time elapsed before surgery; morbidity; and mortality. Patients in the TAC group received similar amounts of preoperative (4.1 +/- 0.8 units) and total (6.6 +/- 1.3 units) blood transfusions compared to the LIM group (3.3 +/- 0.4 units and 5.3 +/- 0.6 units). Overall, more time elapsed before surgery in the LIM group (95.4 +/- 13.0 hrs) compared with the TAC group (73.7 +/- 22.2 hrs) (P < 0.05 Student's t test). There was no significant difference in Apache score, age, or morbidity. Mortality rates were similar between the two groups (LIM 15%, TAC 6%). There was no instance of intractable diarrhea postoperatively in either group. The results indicate that TAC is a safe method of treating massive LGI hemorrhage.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

下消化道(LGI)出血的术前定位一直受到提倡,其依据是与结肠次全切除术相比,有限的结肠切除术与更低的发病率和死亡率相关。然而,广泛的术前评估,尤其是结果为阴性时,可能会不必要地延迟对正在出血患者的手术治疗。本研究的目的是分析在进行大规模LGI出血手术时,全腹结肠切除术(TAC)与有限结肠切除术(LIM)相关的死亡率和发病率。对5年内因大规模LGI出血(术前输注≥1单位浓缩红细胞(PRBC))入院的61例患者进行了分析。收集了以下数据:术前PRBC量;总PRBC量;急性生理与慢性健康状况评分系统(Apache)评分;年龄;切除类型(LIM [n = 42] 与TAC [n = 19]);手术前经过的时间;发病率;以及死亡率。与LIM组(3.3±0.4单位和5.3±0.6单位)相比,TAC组患者术前(4.1±0.8单位)和总共(6.6±1.3单位)接受的输血量相似。总体而言,LIM组手术前经过的时间(95.4±13.0小时)比TAC组(73.7±22.2小时)更长(P < 0.05,学生t检验)。Apache评分、年龄或发病率无显著差异。两组的死亡率相似(LIM组15%,TAC组6%)。两组术后均未出现顽固性腹泻的情况。结果表明,TAC是治疗大规模LGI出血的一种安全方法。(摘要截短至250字)

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