Sosniak W A, Kaye W E, Gomez T M
Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia.
Arch Environ Health. 1994 Jul-Aug;49(4):251-5. doi: 10.1080/00039896.1994.9937475.
Data from the 1988 National Maternal and Infant Health Survey files were linked with data from the 1990 Environmental Protection Agency National Priorities List of hazardous waste sites to determine whether any relationship existed between living in proximity to hazardous waste sites and low birthweight. The odds ratio for low birthweight versus normal birthweight was 1.03 (95% confidence interval [95% CI] = 0.98-1.16), and remained at 0.99 (95% CI = 0.86-1.16) when adjusted for maternal age, parity, infant sex, prenatal care, and behavioral and socioeconomic factors. Very low birthweight, infant and fetal death, prematurity, and congenital malformation were not found to be associated with living in the vicinity of a hazardous waste site during pregnancy. Merging a large population database with environmental data proved to be an innovative but not very efficient method of assessing the risks of low birthweight related to the environment.
1988年全国母婴健康调查档案中的数据与1990年美国环境保护局危险废物场地国家优先清单中的数据相关联，以确定居住在危险废物场地附近与低出生体重之间是否存在任何关系。低出生体重与正常出生体重的比值比为1.03（95%置信区间[95%CI]=0.98 - 1.16），在对产妇年龄、产次、婴儿性别、产前护理以及行为和社会经济因素进行调整后，该比值比仍为0.99（95%CI = 0.86 - 1.16）。未发现极低出生体重、婴儿和胎儿死亡、早产以及先天性畸形与孕期居住在危险废物场地附近有关。将大型人口数据库与环境数据合并被证明是一种评估与环境相关的低出生体重风险的创新但效率不高的方法。
