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大面积肺栓塞外科治疗中的决策制定

Decision making in the surgical treatment of massive pulmonary embolism.

作者信息

Stulz P, Schläpfer R, Feer R, Habicht J, Grädel E

机构信息

Cardio-thoracic Unit, University Hospital, Basel, Switzerland.

出版信息

Eur J Cardiothorac Surg. 1994;8(4):188-93. doi: 10.1016/1010-7940(94)90113-9.

Abstract

Pulmonary embolectomy in the treatment of acute massive pulmonary embolism (PE) is the subject of considerable controversy with regard to indication, technique of embolectomy and perioperative management. Since 1968 50 patients have undergone surgery for massive PE in our unit. Inflow occlusion technique and cardiopulmonary bypass were used in 33 and 17 patients, respectively. The overall operative mortality was 46%. Univariate analysis disclosed age (< 60 vs > 60), preoperative hemodynamics (cardiogenic shock vs cardiac arrest), location of emboli (peripheral vs central), duration of symptoms (hours vs days vs weeks) and number of episodes (first episode vs recurrent pulmonary emboli) as predictive factors of the post-operative outcome. The results of the retrospective analysis show that pulmonary embolectomy remains an acceptable procedure in patients with acute massive pulmonary emboli who are in refractory cardiogenic shock or who need intermittent resuscitation.

摘要

肺栓子切除术治疗急性大面积肺栓塞(PE)在适应证、栓子切除技术及围手术期管理方面存在诸多争议。自1968年以来,我院有50例患者接受了大面积PE手术。分别有33例和17例患者采用了入路阻断技术和体外循环。总体手术死亡率为46%。单因素分析显示年龄(<60岁与>60岁)、术前血流动力学(心源性休克与心脏骤停)、栓子位置(外周与中央)、症状持续时间(小时与天与周)及发作次数(首次发作与复发性肺栓塞)是术后结果的预测因素。回顾性分析结果表明,对于处于难治性心源性休克或需要间歇性复苏的急性大面积肺栓塞患者,肺栓子切除术仍是一种可接受的手术。

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