Gajdos P
Service de Réanimation Médicale, Hôpital Raymond Poincaré, Garches, France.
Clin Exp Immunol. 1994 Jul;97 Suppl 1(Suppl 1):49-51.
Myasthenia gravis (MG) is an autoimmune disease of neuromuscular transmission associated with the presence of anti-acetylcholine receptor antibodies (anti-AChR Ab). Current treatment of MG includes anti-cholinesterase drugs, thymectomy, corticosteroids, immunosuppressants and plasma exchange (PE). The use of intravenous immune globulin (IVIG) in MG was proposed 10 years ago. Published results of IVIG treatment are discussed and the need for a controlled study is emphasized.
重症肌无力(MG)是一种与抗乙酰胆碱受体抗体(抗AChR Ab)存在相关的神经肌肉传递自身免疫性疾病。MG的当前治疗方法包括抗胆碱酯酶药物、胸腺切除术、皮质类固醇、免疫抑制剂和血浆置换(PE)。静脉注射免疫球蛋白(IVIG)用于MG的治疗是10年前提出的。本文讨论了IVIG治疗已发表的结果,并强调了进行对照研究的必要性。