Nofzinger E A, Schwartz R M, Reynolds C F, Thase M E, Jennings J R, Frank E, Fasiczka A L, Garamoni G L, Kupfer D J
Sleep and Chronobiology Center, University of Pittsburgh School of Medicine, Pennsylvania 15213.
J Consult Clin Psychol. 1994 Feb;62(1):83-91. doi: 10.1037//0022-006x.62.1.83.
This article explored the relationship between daytime affect and REM sleep in 45 depressed men before and after treatment with cognitive-behavioral therapy and in a control group of 43 healthy subjects. The intensity of daytime affect (as measured by the sum of positive and negative affects) in depressed men correlated significantly and positively with phasic REM sleep measures at both pre- and posttreatment. This relationship was not found in healthy control subjects. In depressed men, both affect intensity and phasic REM sleep measures decreased over the course of treatment. The results suggest a relationship between phasic REM sleep and intensity of affect reported by depressed men. On the basis of this preliminary observation, it was hypothesized that abnormalities in phasic REM sleep in depressed patients are related, in part, to fundamental alterations in the intensity of their affective experience.
本文探讨了45名抑郁症男性在接受认知行为治疗前后的日间情绪与快速眼动睡眠（REM睡眠）之间的关系，并与43名健康受试者组成的对照组进行了比较。抑郁症男性的日间情绪强度（通过积极情绪和消极情绪的总和来衡量）在治疗前和治疗后均与快速眼动睡眠的阶段性指标显著正相关。在健康对照组中未发现这种关系。在抑郁症男性中，情绪强度和快速眼动睡眠的阶段性指标在治疗过程中均有所下降。结果表明，抑郁症男性报告的快速眼动睡眠阶段性指标与情绪强度之间存在关联。基于这一初步观察，推测抑郁症患者快速眼动睡眠的异常部分与他们情感体验强度的根本改变有关。
