Henigst W, Klose P, Paulig R
MMW Munch Med Wochenschr. 1975 Jan 17;117(3):83-6.
Over several years we have determined the titers of the neutralizing antibodies against the three types of polio virus in 147 adult females working in hospitals or laboratories. Through administration of a trivalent oral vaccine we attempted to boost the vaccination and supplement the missing antibodies. A strong antibody reaction against all three types of polio virus could only be obtained usually after an additional parenteral injection of inactivated serum. Four cases are described in detail as rare occurrences (2.7 percent of those investigated). For some unknown reason, the desired antibody formation could not be obtained in these subjects in spite of repeated administration of both types of vaccine.
在几年时间里，我们测定了147名在医院或实验室工作的成年女性体内针对三种脊髓灰质炎病毒的中和抗体滴度。通过口服三价疫苗，我们试图加强免疫接种并补充缺失的抗体。通常只有在额外注射一针灭活血清后，才能获得针对所有三种脊髓灰质炎病毒的强烈抗体反应。详细描述了4例罕见病例（占被调查者的2.7%）。出于某种未知原因，尽管对这些受试者反复接种了两种疫苗，仍未能产生预期的抗体。
