Krakhmaleva I N, Vlasov V I, Telesnina G N, Krasnova T P, Vladimirov A V, Sazykin Iu O
Antibiot Khimioter. 1993 Aug-Sep;38(8-9):11-5.
The activities of the key glycolytic enzymes i.e. hexokinase, phosphofructokinase, pyruvate kinase and lactate dehydrogenase were detected and investigated in 3 strains of Streptomyces rimosus differing in the level of the oxytetracycline production. The samples were assayed at different fermentation stages and under different aeration conditions. Correlation between the level of the pyruvate kinase activity within the first days of the fermentation process and the strain capacity for the antibiotic accumulation at the final stage of the fermentation process was observed.
在3株土霉素产量水平不同的龟裂链霉菌菌株中，检测并研究了关键糖酵解酶即己糖激酶、磷酸果糖激酶、丙酮酸激酶和乳酸脱氢酶的活性。在不同发酵阶段和不同通气条件下对样品进行了测定。观察到发酵过程最初几天内丙酮酸激酶活性水平与发酵过程最后阶段抗生素积累的菌株能力之间的相关性。
