Guidotti T L, Jhangri G S
Department of Public Health Sciences, University of Alberta, Edmonton, Canada.
J Asthma. 1994;31(4):277-90. doi: 10.3109/02770909409089475.
Mortality from asthma has been reported to be increasing in recent years in many countries, including Canada. Alberta, and the prairie provinces generally, appear to have an excess of deaths from asthma compared to other provinces. We studied mortality from asthma and from chronic obstructive pulmonary disease (COPD) generally in Alberta between 1927 and 1987 using a data set compiled and recorded from Alberta Vital Statistics to describe birth cohorts' age-specific mortality rates. We also present the distribution of deaths in the years since 1987. There was a clear and sustained increase in mortality from COPD since 1950 after age 40 but no evidence to support the proposition that deaths from asthma were increasing in recent years; more recent data from Alberta Vital Statistics show no sustained increase since 1987, either. There was great variability from year to year and sporadically increased rates in a given year that were not sustained. These transient increases were observed particularly among females aged 10-14, 15-19, and 25-29 and among males aged 15-19, 25-29, and 80-84; however, there were also comparable decreases in asthma mortality of similar magnitude during the same time period in different age groups or in the other sex in the age group 10-14. We conclude that there is no excess of deaths from asthma over those expected by historical trends in Alberta at the present time but that the smoking-related epidemic of deaths from COPD continues unabated. The "smoothness" and consistency of the mortality trends suggest that physicians certifying deaths from these causes are using implicit diagnostic criteria that have not changed abruptly.
据报道,近年来包括加拿大在内的许多国家哮喘死亡率都在上升。与其他省份相比,艾伯塔省以及整个草原省份的哮喘死亡人数似乎过多。我们利用从艾伯塔省生命统计数据汇编和记录的数据集,研究了1927年至1987年期间艾伯塔省哮喘和慢性阻塞性肺疾病(COPD)的总体死亡率,以描述出生队列的年龄别死亡率。我们还展示了1987年以来各年份的死亡分布情况。自1950年以来,40岁以后COPD死亡率有明显且持续的上升,但没有证据支持近年来哮喘死亡人数在增加这一观点;艾伯塔省生命统计的最新数据也显示自1987年以来没有持续上升。每年都有很大的变异性,某一年偶尔会出现上升但无法持续。这些短暂的上升尤其在10 - 14岁、15 - 19岁和25 - 29岁的女性以及15 - 19岁、25 - 29岁和80 - 84岁的男性中观察到;然而,在同一时期不同年龄组或10 - 14岁年龄组的另一性别中,哮喘死亡率也有类似幅度的下降。我们得出结论,目前艾伯塔省哮喘死亡人数并未超过历史趋势预期的人数,但与吸烟相关的COPD死亡流行仍在持续。死亡率趋势的“平滑性”和一致性表明,开具这些死因证明的医生使用的隐含诊断标准没有突然改变。