Shalev H, Ohali M, Abramson O
Ben-Gurion University School of Medicine, Pediatric Diagnostic and Therapeutic Center, Soroka Medical Center, Beer-Sheva, Israel.
J Pediatr. 1994 Aug;125(2):246-8. doi: 10.1016/s0022-3476(94)70204-7.
We report four patients with pseudohypoaldosteronism, aged 5 months to 5 years. All patients had hypercalciuria and three had nephrocalcinosis. Two patients with nephrocalcinosis were treated with indomethacin. Polydipsia decreased and appetite and weight gain improved within 14 days of therapy. Hypercalciuria, polyuria, and creatinine clearance decreased 30% to 50% and urinary prostaglandin E2 levels decreased fourfold to eightfold.
我们报告了4例年龄在5个月至5岁之间的假性醛固酮减少症患者。所有患者均有高钙尿症，其中3例有肾钙质沉着症。2例肾钙质沉着症患者接受了吲哚美辛治疗。治疗14天内，烦渴减轻，食欲和体重增加。高钙尿症、多尿和肌酐清除率下降了30%至50%，尿前列腺素E2水平下降了4至8倍。
