Rikkers L F, Jin G
Department of Surgery, University of Nebraska Medical Center, Omaha.
Gastroenterol Clin North Am. 1993 Dec;22(4):821-42.
Surgical options for management of variceal hemorrhage include portosystemic shunts (nonselective and selective), nonshunting operations, and hepatic transplantation. In most centers, operations that preserve hepatic portal perfusion (selective shunt and nonshunting operations) have replaced nonselective shunts as the most commonly performed surgical procedures. The results of multiple controlled trials suggest that the frequency of postshunt encephalopathy is less after the distal splenorenal shunt than after the nonselective shunts. Hepatic transplantation should be considered as initial therapy for nonalcoholic cirrhotics and abstinent alcoholic cirrhotics with variceal hemorrhage or advanced liver disease and without contraindications.
治疗静脉曲张出血的手术选择包括门体分流术(非选择性和选择性)、非分流手术以及肝移植。在大多数中心,保留肝门静脉灌注的手术(选择性分流和非分流手术)已取代非选择性分流术,成为最常施行的外科手术。多项对照试验结果表明,远端脾肾分流术后分流后脑病的发生率低于非选择性分流术后。对于非酒精性肝硬化患者以及已戒酒的酒精性肝硬化合并静脉曲张出血或晚期肝病且无禁忌证的患者,应考虑将肝移植作为初始治疗方法。