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肝外门静脉高压症及静脉曲张出血的外科治疗

Surgical management of extrahepatic portal hypertension and variceal bleeding.

作者信息

Orozco H, Takahashi T, Mercado M A, Prado E, Chan C

机构信息

Department of Surgery, Instituto Nacional de la Nutricion Salvador Zubiran, Tlalpan, Mexico City, D.F., Mexico.

出版信息

World J Surg. 1994 Mar-Apr;18(2):246-50. doi: 10.1007/BF00294409.

DOI:10.1007/BF00294409
PMID:8042330
Abstract

Variceal bleeding remains an important complication in extrahepatic portal vein thrombosis (EPVT). As for portal hypertension due to other etiologies, an elective treatment to decrease the risk of subsequent rebleeding is warranted. The results of the Sugiura-Futagawa procedure (SP) in 38 patients with variceal bleeding secondary to EPVT are reported: 20 women and 18 men, with a mean age of 28 +/- 2 years (SEM). Thirty-seven patients were classified as Child-Pugh class A, and one patient as class B. In terms of diagnosis, 45% of patients had idiopathic EPVT, and 18% had associated hypercoagulability disorders; 52% of patients had associated splenic vein thrombosis. The SP was completed in two surgical stages in 18 patients and in one surgical stage in 14; 6 patients had only the abdominal stage. One patient had mild postoperative encephalopathy, and three patients rebled at long-term follow-up study. There were two operative deaths. Actuarial survival was 70% at 64 months. It is concluded that the SP is an excellent alternative for patients with variceal bleeding secondary to EPVT.

摘要

静脉曲张出血仍是肝外门静脉血栓形成(EPVT)的一项重要并发症。对于由其他病因引起的门静脉高压症,进行择期治疗以降低后续再出血风险是必要的。本文报告了38例继发于EPVT的静脉曲张出血患者接受杉浦-二川手术(SP)的结果:其中女性20例,男性18例,平均年龄28±2岁(标准误)。37例患者为Child-Pugh A级,1例为B级。在诊断方面,45%的患者为特发性EPVT,18%的患者伴有高凝性疾病;52%的患者伴有脾静脉血栓形成。18例患者分两个手术阶段完成SP,14例在一个手术阶段完成;6例仅进行了腹部手术阶段。1例患者术后出现轻度脑病,3例患者在长期随访研究中再次出血。有2例手术死亡。64个月时的精算生存率为70%。结论是,对于继发于EPVT的静脉曲张出血患者,SP是一种很好的治疗选择。

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本文引用的文献

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Surgical Treatment of Portal Hypertension According to State of Intrahepatic Circulation.根据肝内循环状态进行门静脉高压症的外科治疗。
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Liver pathology of idiopathic portal hypertension. Comparison with non-cirrhotic portal fibrosis of India. The Japan idiopathic portal hypertension study.特发性门静脉高压症的肝脏病理学。与印度非肝硬化性门脉纤维化的比较。日本特发性门静脉高压症研究。
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Transabdominal modified devascularization procedure with or without esophageal stapler transection--an operation adequate for effective control of a variceal bleed. Is esophageal stapler transection necessary?经腹改良去血管化手术(伴或不伴食管吻合器横断术)——一种有效控制静脉曲张出血的手术方式。食管吻合器横断术是否必要?
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Etiology and consequences of thrombosis in abdominal vessels.腹部血管血栓形成的病因及后果。
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Extra- and intrahepatic portal hypertension without cirrhosis (hepatoportal sclerosis).无肝硬化的肝内外门静脉高压症(肝门静脉硬化症)
Ann Surg. 1965 Oct;162(4):602-20. doi: 10.1097/00000658-196510000-00006.
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Obliterative portal venopathy of the liver. Associated with so-called idiopathic portal hypertension or tropical splenomegaly.肝脏闭塞性门静脉病。与所谓的特发性门静脉高压或热带脾肿大相关。
Arch Pathol. 1969 Apr;87(4):359-69.
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"Idiopathic" portal hypertension due to occlusion of intrahepatic portal veins by organized thrombi. A study based on postmortem vinylite-injection corrosion and dissection of the intrahepatic vasculature in 4 cases.由机化血栓阻塞肝内门静脉引起的“特发性”门静脉高压症。一项基于4例尸体死后用乙烯基树脂注射腐蚀及肝内血管系统解剖的研究。
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