Tomberg T A, Miagi M A, Kauba T F, Rekand T E, Kaasik A E
Zh Nevrol Psikhiatr Im S S Korsakova. 1993;93(3):15-8.
Before and after intravenous administration of 1-1.5 mg nimotop 18 patients with acute brain infarction underwent EEG, integral body rheography, computed tomography and measurement of regional volumetric cerebral circulation (RVCC). Nimotop appeared to increase RVCC in the infarction zone, especially in low initial RVCC levels. The drug induced a shift to EEG normalization and a hypotensive effect, cerebral hemodynamics remaining without changes. Nimodipine-type calcium antagonists favourably affect brain perfusion and bioelectric activity which is promising for application in acute cerebral infarction.
18例急性脑梗死患者在静脉注射1 - 1.5毫克尼莫通前后，接受了脑电图、全身血流图、计算机断层扫描以及局部脑血容量（RVCC）测量。尼莫通似乎能增加梗死区域的RVCC，尤其是在初始RVCC水平较低时。该药物使脑电图趋向正常化，并产生降压作用，而脑血流动力学保持不变。尼莫地平类钙拮抗剂对脑灌注和生物电活动有积极影响，有望应用于急性脑梗死。
