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Studies on the effect of an heterologous fatty acid-binding protein on acyl-CoA oxidase induction in Saccharomyces cerevisiae.

作者信息

Smaczyńska I, Skoneczny M, Kurlandzka A

机构信息

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa.

出版信息

Biochem J. 1994 Jul 15;301 ( Pt 2)(Pt 2):615-20. doi: 10.1042/bj3010615.

DOI:10.1042/bj3010615
PMID:8043008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1137125/
Abstract

The participation of fatty acid-binding protein (FABP) in the induction of peroxisomal beta-oxidation of fatty acids was investigated in vivo in an heterologous system. Bovine heart FABP was expressed in Saccharomyces cerevisiae under the control of two different promoters: a constitutive one and an oleic acid-inducible one. Constructs were introduced into yeast cells on multicopy and integrating plasmids. The heterologous FABP was present in yeast cells in two isoforms having pI values of about 5 and was able to bind oleic acid. The heterologous FABP had no significant effect on acyl-CoA oxidase activity at various concentrations of the inducing agent.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/1137125/334ebd35bc04/biochemj00083-0297-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/1137125/079a1755a17e/biochemj00083-0296-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/1137125/334ebd35bc04/biochemj00083-0297-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/1137125/079a1755a17e/biochemj00083-0296-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/1137125/334ebd35bc04/biochemj00083-0297-a.jpg

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Studies on the effect of an heterologous fatty acid-binding protein on acyl-CoA oxidase induction in Saccharomyces cerevisiae.
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本文引用的文献

1
A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase.一种用于测量过氧化氢被过氧化氢酶分解的分光光度法。
J Biol Chem. 1952 Mar;195(1):133-40.
2
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
3
Isoforms of fatty-acid-binding protein in bovine heart are coded by distinct mRNA.
Eur J Biochem. 1993 Aug 1;215(3):555-9. doi: 10.1111/j.1432-1033.1993.tb18065.x.
4
N-terminal variants of fatty acid-binding protein from bovine heart overexpressed in Escherichia coli.在大肠杆菌中过表达的牛心脂肪酸结合蛋白的N端变体。
J Biotechnol. 1994 Apr 15;33(3):259-69. doi: 10.1016/0168-1656(94)90074-4.
5
Possible involvement of fatty acid binding protein in peroxisomal beta-oxidation of fatty acids.脂肪酸结合蛋白可能参与脂肪酸的过氧化物酶体β-氧化。
Biochim Biophys Acta. 1980 Jan 18;617(1):156-60. doi: 10.1016/0005-2760(80)90233-7.
6
Metabolic pathways in peroxisomes and glyoxysomes.过氧化物酶体和乙醛酸循环体中的代谢途径。
Annu Rev Biochem. 1981;50:133-57. doi: 10.1146/annurev.bi.50.070181.001025.
7
Peroxisomal beta-oxidation in brown fat.棕色脂肪中的过氧化物酶体β-氧化
Ann N Y Acad Sci. 1982;386:40-58. doi: 10.1111/j.1749-6632.1982.tb21406.x.
8
Effects of peroxisome proliferators on fatty acid-binding protein in rat liver.过氧化物酶体增殖剂对大鼠肝脏脂肪酸结合蛋白的影响。
Biochim Biophys Acta. 1983 Nov 1;754(1):21-7. doi: 10.1016/0005-2760(83)90077-2.
9
Transformation of intact yeast cells treated with alkali cations.经碱金属阳离子处理的完整酵母细胞的转化
J Bacteriol. 1983 Jan;153(1):163-8. doi: 10.1128/jb.153.1.163-168.1983.
10
The primary structure of the alcohol dehydrogenase gene from the fission yeast Schizosaccharomyces pombe.来自裂殖酵母粟酒裂殖酵母的乙醇脱氢酶基因的一级结构。
J Biol Chem. 1983 Jan 10;258(1):143-9.