Horn M, Michelini M, Greisler H P, Littooy F N, Baker W H
Department of Surgery, Loyola University Medical Center, Stritch School of Medicine, Maywood, Ill. 60153.
Ann Vasc Surg. 1994 May;8(3):221-4. doi: 10.1007/BF02018167.
The classic workup of patients considered for carotid endarterectomy (CE) has included contrast arteriography to delineate the nature and extent of the arterial pathology. Noninvasive testing (NIT) consisting of duplex scanning plus sound spectrum analysis is an alternative method for accurately evaluating the carotid bifurcation. The accuracy of our laboratory in comparing NIT to contrast arteriography has been established by use of the guidelines suggested by the Intersocietal Commission for the Accreditation of Vascular Laboratories. Forty-two patients underwent CE based on NIT alone. Seventeen had hemispheric transient ischemic attacks or minor strokes, six had amaurosis fugax, three had nonspecific symptoms, and 16 were asymptomatic. NIT identified a severe stenosis that was limited to the carotid bifurcation; the internal carotid artery distal to the bulb was normal. The predicted stenotic atherosclerotic lesion was confirmed at operation in all patients. One patient had a high bifurcation that required an extension of the original incision. Of three undiagnosed kinked distal internal carotid arteries found at operation, only one required surgical correction. No transient ischemic attacks, strokes, or deaths occurred postoperatively. CE can be performed in selected patients based on NIT alone, obviating the mortality, morbidity, and cost of arteriography. This algorithm demands that the NIT is unequivocal and the accuracy of the testing laboratory is established and maintained according to published standards.
对于考虑行颈动脉内膜切除术(CE)的患者,传统的检查方法包括行血管造影以明确动脉病变的性质和范围。由双功扫描加频谱分析组成的无创检测(NIT)是准确评估颈动脉分叉处的另一种方法。我们实验室通过采用血管实验室认证协会建议的指南,确定了将NIT与血管造影进行比较的准确性。42例患者仅根据NIT接受了CE。17例有半球性短暂性脑缺血发作或轻度中风,6例有一过性黑矇,3例有非特异性症状,16例无症状。NIT发现严重狭窄局限于颈动脉分叉处;球部远端的颈内动脉正常。所有患者手术中均证实了预测的狭窄性动脉粥样硬化病变。1例患者有高位分叉,需要延长原切口。手术中发现3例未诊断出的颈内动脉远端扭曲,只有1例需要手术矫正。术后未发生短暂性脑缺血发作、中风或死亡。CE可以仅基于NIT在选定的患者中进行,从而避免血管造影的死亡率、发病率和费用。该算法要求NIT明确,并且检测实验室的准确性要根据已发表的标准来确立和维持。