痴呆症中的血小板单胺氧化酶B活性与维生素B12

Platelet monoamine oxidase B activity and vitamin B12 in dementia.

作者信息

Fischer P, Götz M E, Ellinger B, Streifler M, Riederer P, Danielczyk W

机构信息

Psychiatric Clinic, University of Vienna, Austria.

出版信息

Biol Psychiatry. 1994 May 15;35(10):772-4. doi: 10.1016/0006-3223(94)91138-x.

DOI:10.1016/0006-3223(94)91138-x

PMID:8043706

Abstract

The activity of platelet monoamine oxidase B (MAO-B) was highly correlated with the severity of dementia in 39 patients suffering from probable dementia of the Alzheimer type and in 18 age-matched controls. There was no association between a low vitamin B12 level and high MAO-B activity in our sample of patients, who are living in a geriatric hospital where the balanced nutrition of inpatients is controlled by diet assistants.

摘要

在39例可能患有阿尔茨海默型痴呆的患者以及18例年龄匹配的对照者中，血小板单胺氧化酶B（MAO-B）的活性与痴呆严重程度高度相关。在我们居住于老年医院的患者样本中，低维生素B12水平与高MAO-B活性之间没有关联，该医院住院患者的营养均衡由饮食助理控制。