Levkova N A, Kakabadze S A, Tepliakova N P, Lekoev G Z
Biull Eksp Biol Med. 1981 Feb;91(2):231-3.
Experiments on rats under 30-day hypokinesia have shown an increase in the mitochondrial area in perinuclear, myofibrillar and subsarcolemmal zones of the cardiomyocyte pericaryon, accompanied by a concurrent rise in the number of crests. The crest density index and the amount of mitochondria in te pericaryon diminish. These changes are considered as compensatory-adaptive reconstitution of hypertrophic nature in response to partial destruction of mitochondria. During the observation period this reconstitution is not completed and thus underlies the decreased contractility and functional reserves of the heart in hypokinesia.
对大鼠进行30天运动不足实验显示，心肌细胞核周、肌原纤维和肌膜下区域的线粒体面积增加，同时嵴的数量也相应增加。细胞核周的嵴密度指数和线粒体数量减少。这些变化被认为是对线粒体部分破坏的一种肥大性质的代偿性适应重建。在观察期内，这种重建尚未完成，因此是运动不足时心脏收缩力和功能储备下降的基础。
