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从大鼠胰腺获得的新胰岛不含过客白细胞。

[Neoislets obtained from rat pancreas do not contain passenger leukocytes].

作者信息

Ablamunits V G, Baranova F S

出版信息

Biull Eksp Biol Med. 1993 May;115(5):502-4.

PMID:8043834
Abstract

Reaggregation of pancreatic islet cells during their cultivation in stationary culture leads to formation of neoislets--compact insulin secreting clusters. By the means of indirect immunofluorescence it has been shown that neoislets have no leukocytes-passengers, common for normal islets and responsible for allograft rejection.

摘要

胰腺胰岛细胞在静态培养过程中的重新聚集会导致新胰岛的形成,即紧密的胰岛素分泌簇。通过间接免疫荧光法已表明,新胰岛没有白细胞过客,而白细胞过客在正常胰岛中常见且是同种异体移植排斥反应的原因。

相似文献

1
[Neoislets obtained from rat pancreas do not contain passenger leukocytes].从大鼠胰腺获得的新胰岛不含过客白细胞。
Biull Eksp Biol Med. 1993 May;115(5):502-4.
2
[Aggregates of islet cells, their structure and insulin-producing activity during cultivation in vitro].[胰岛细胞聚集体、其在体外培养期间的结构及胰岛素分泌活性]
Biull Eksp Biol Med. 1990 Dec;110(12):650-3.
3
Analysis of morphological and functional maturation of neoislets generated in vitro from pancreatic ductal cells and their suitability for islet banking and transplantation.体外由胰腺导管细胞生成的新胰岛的形态学和功能成熟分析及其对胰岛储存和移植的适用性
J Endocrinol. 2004 Jul;182(1):105-12. doi: 10.1677/joe.0.1820105.
4
Immobilized hemoglobin improves islet function and viability in the bioartificial pancreas in vitro and in vivo.固定化血红蛋白在体外和体内均可改善生物人工胰腺中的胰岛功能和活力。
Transplant Proc. 1994 Apr;26(2):792-800.
5
[Impact of islet alpha cell loss on insulin secretion].[胰岛α细胞丢失对胰岛素分泌的影响]
Zhonghua Yi Xue Za Zhi. 2002 Oct 25;82(20):1427-31.
6
Allotransplantation of islet endocrine aggregates.胰岛内分泌聚集体的同种异体移植。
Diabetes. 1987 Mar;36(3):315-9. doi: 10.2337/diab.36.3.315.
7
Generation of human islets through expansion and differentiation of non-islet pancreatic cells discarded (pancreatic discard) after islet isolation.通过胰岛分离后废弃的非胰岛胰腺细胞(胰腺废弃组织)的扩增和分化来生成人胰岛。
Pancreas. 2006 Mar;32(2):130-8. doi: 10.1097/01.mpa.0000202945.78331.93.
8
Generation of functional islet-like clusters after monolayer culture and intracapsular aggregation of adult human pancreatic islet tissue.成人人类胰岛组织单层培养和囊内聚集后功能性胰岛样簇的生成。
Transplantation. 2007 Mar 27;83(6):685-93. doi: 10.1097/01.tp.0000256178.57359.4f.
9
[Allotransplantation of islet endocrine aggregates].胰岛内分泌聚集体的同种异体移植
Nihon Geka Gakkai Zasshi. 1988 Feb;89(2):245-50.
10
Scale production of porcine isletlike cell clusters and xenotransplantation.
Transplant Proc. 1992 Oct;24(5):2001.

引用本文的文献

1
Low energy X-ray (grenz ray) treatment of purified islets prior to allotransplant markedly decreases passenger leukocyte populations.在同种异体移植前,对纯化胰岛进行低能X射线(格伦茨射线)治疗可显著减少过客白细胞群体。
Islets. 2017 Jul 4;9(4):e1330742. doi: 10.1080/19382014.2017.1330742. Epub 2017 Jul 10.