Zhao L, Zhang Y, Xu Z X
3rd Teaching Hospital of Norman Bethune Univ. of Med. Sci, Changchun.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Feb;14(2):71-3, 67.
Xijian Tongshuan pill (XJTS), consisted of Siegesbeckia orientalis, Moschus moschiferus, Hirudo nipponica, Prunus Persicae, Carthamus tinctoruis, Ligusticum wallichi, Panax notoginseng, Angelica Sinensis, Borneolum, etc, were used in treating 70 patients with cerebral thrombosis. The marked effective rate was 82.9%, total effective rate was 96.7%. In control group A, Dextranum and Venoruton were used, in control group B cyclandelate capsule were used. The marked effective rate was 61.7% and 61.1% respectively, the total effective rate was 81.7% and 83.3%. The differences were significant (P < 0.01). The improvement of blood rheology and CT of brain were also significant (P < 0.01). The experiment proved that XJTS pill could inhibit and delay the thrombosis of rabbit, inhibit the platelet aggregation. Acute and subacute toxicity tests proved that XJTS pill was safe and effective.
稀健通栓丸由豨莶草、麝香、水蛭、桃仁、红花、川芎、三七、当归、冰片等组成,用于治疗70例脑血栓患者。显效率为82.9%,总有效率为96.7%。A对照组使用右旋糖酐和维脑路通,B对照组使用环扁桃酯胶囊。显效率分别为61.7%和61.1%,总有效率分别为81.7%和83.3%。差异有统计学意义(P<0.01)。血液流变学和脑部CT的改善也有统计学意义(P<0.01)。实验证明,稀健通栓丸能抑制和延缓家兔血栓形成,抑制血小板聚集。急性和亚急性毒性试验证明稀健通栓丸安全有效。