Schag C A, Ganz P A, Wing D S, Sim M S, Lee J J
Department of Medicine, UCLA School of Medicine 90024.
Qual Life Res. 1994 Apr;3(2):127-41. doi: 10.1007/BF00435256.
In a cross-sectional study design, a disease free sample of 57 lung, 117 colon, and 104 prostate cancer survivors who represented short, intermediate and long-term survivors completed a detailed assessment of quality of life (QOL) and rehabilitation needs using the CAncer Rehabilitation Evaluation System (CARES). Demographic and medical data, social support, and a global QOL rating were also assessed. Lung cancer patients showed no differences in QOL with respect to their period of survival. QOL improved for survivors of colon cancer as they lived for longer periods, but declined with time for survivors of prostate cancer. The best predictor of QOL for all groups was KPS, although other variables such as type of hospital, gender, and work status were predictive for survivors of colon cancer. For survivors of prostate cancer comorbidity with other medical illnesses, time since diagnosis and comorbidity due to psychiatric difficulties were predictive of QOL. All groups had significant rehabilitation problems in the domains of physical, psychosocial, sexual, medical interaction, and marital relationships. Lung cancer survivors had more problems than the other cancer survivors. We conclude that patients who survive cancer do not return to a state of normal health. They demonstrate a variety of difficulties with which they must cope as they continue to survive. Greater efforts need to be made early in diagnosis and treatment to understand rehabilitation problems and target interventions in the hope of reducing later sequelae.
在一项横断面研究设计中,选取了57名肺癌、117名结肠癌和104名前列腺癌幸存者组成的无疾病样本,这些幸存者分别代表短期、中期和长期幸存者,他们使用癌症康复评估系统(CARES)完成了生活质量(QOL)和康复需求的详细评估。还评估了人口统计学和医学数据、社会支持以及总体生活质量评分。肺癌患者在生活质量方面在生存期限上没有差异。结肠癌幸存者的生活质量随着生存时间延长而改善,但前列腺癌幸存者的生活质量则随时间下降。所有组生活质量的最佳预测指标是KPS,尽管其他变量如医院类型、性别和工作状态对结肠癌幸存者具有预测性。对于前列腺癌幸存者,合并其他疾病、确诊后的时间以及因精神问题导致的合并症对生活质量具有预测性。所有组在身体、心理社会、性、医疗互动和婚姻关系等领域都存在显著的康复问题。肺癌幸存者比其他癌症幸存者有更多问题。我们得出结论,癌症幸存者不会恢复到正常健康状态。他们表现出各种困难,在继续生存过程中必须应对这些困难。在诊断和治疗早期需要做出更大努力,以了解康复问题并针对性地进行干预,希望减少后期后遗症。